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K. V. Galaktionov 《Biology Bulletin》2016,43(9):1129-1147
The review deals with the biodiversity, life cycles, distribution and temperature adaptations of parasites circulating in the coastal waters of northern polar seas. Special attention is given to helminths of marine birds, which are the most common parasites in the coastal waters. Among them, the focus is on trematodes. Factors responsible for the impoverished species composition of parasites in the Arctic are analyzed. It is shown that species without free-living larvae in the life cycle have an advantage in this environment. The abundance of cestodes and acanthocephalans in Arctic seabirds is linked with the high proportion of crustaceans in their diet. The phenomenon of nonspecific parasitism (occurrence of parasites in atypical host species) is analyzed from an evolutionary viewpoint. Characteristic features in the spatial distribution of infection of marine coastal invertebrates with parasite larvae are considered, and factors that determine it are specified. The prevalence of infection in intermediate hosts is closely connected with the abundance of final hosts, which makes it possible to estimate the abundance of final hosts in a given region and reveal trends in its changes. Trematodes have a high potential for temperature acclimation. This facilitates their transmission in the northern seas but, on the other hand, makes it unlikely that the transmission process would be intensified upon an increase in summer temperatures resulting from climate warming. However, intensification of transmission may well occur due to the prolongation of the warm season (“transmission window”), which has been predicted and is already observed. It is suggested that warming in the Arctic promotes both the entry of certain “southern” species into the Arctic and the trans-Arctic interpenetration of the North Atlantic and North Pacific parasitic faunas. A case is made for the necessity to broaden the scope of parasitological research in the Arctic and Subarctic, including parasitological monitoring at the reference sites of the sea coast. 相似文献
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Katherine E. Price Giulia Orazi Kathryn L. Ruoff Wesley P. Hebert George A. O’Toole Paul Mastoridis 《PloS one》2015,10(10)
Cystic Fibrosis (CF) is a human genetic disease that results in the accumulation of thick, sticky mucus in the airways, which results in chronic, life-long bacterial biofilm infections that are difficult to clear with antibiotics. Pseudomonas aeruginosa lung infection is correlated with worsening lung disease and P. aeruginosa transitions to an antibiotic tolerant state during chronic infections. Tobramycin is an aminoglycoside currently used to combat lung infections in individuals with CF. While tobramycin is effective at eradicating P. aeruginosa in the airways of young patients, it is unable to completely clear the chronic P. aeruginosa infections in older patients. A recent report showed that co-addition of tobramycin and mannitol enhanced killing of P. aeruginosa grown in vitro as a biofilm on an abiotic surface. Here we employed a model system of bacterial biofilms formed on the surface of CF-derived airway cells to determine if mannitol would enhance the antibacterial activity of tobramycin against P. aeruginosa grown on a more clinically relevant surface. Using this model system, which allows the growth of robust biofilms with high-level antibiotic tolerance analogous to in vivo biofilms, we were unable to find evidence for enhanced antibacterial activity of tobramycin with the addition of mannitol, supporting the observation that this type of co-treatment failed to reduce the P. aeruginosa bacterial load in a clinical setting. 相似文献
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Judit Bereczki Jnos P. Tth Gbor Sramk Zoltn Varga 《Journal of Zoological Systematics and Evolutionary Research》2014,52(1):32-43
The main goal of our research was to study comprehensively the differences between the two phenological forms of the socially parasitic and globally threatened Large Blue (Maculinea arion) in the Carpathian Basin using four character sets (mitochondrial sequences, allozymes, male genitalia and wing morphometrics). Comparative analyses of distance matrices, phylogenetic trees and ordination patterns have been applied. The genetic and morphometric patterns revealed by our studies were discordant. While we experienced a significant differentiation between the ‘spring’ and ‘summer type’ of M. arion in both wing and genital traits, the two phenological forms did not show any genetic differentiation on two mitochondrial loci and in allozymes. At the same time, all individuals were infected by Wolbachia. Although certain wing traits may not represent reliable tracers of phylogeny because of the particular adaptive significance, the wing characteristics involved in our research are probably determined genetically. Additionally, the significant differentiation of male genitalia also indicates incipient prezygotic isolation arising from phenological differentiation between the ‘spring and summer arion’. It is possible that all extant differences between the two forms are attributable to (1) different host‐ant use, (2) incipient speciation, (3) cytoplasmatic incompatibility (CI) by Wolbachia or the combination of these factors. In addition, discordant results indicate that the combined use of different approaches and data sets is strictly necessary to clarify systematic and evolutionary relationships. 相似文献
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Tissue specific plant lectins were searched in the seeds of 44 tropical trees of Kerala, India. Seeds of only 12 plant species
showed lectin activity. N-acetyl-D-galactosamine was the best inhibitor of lectin activity for the majority of the seeds.
Lectin activity in the seeds of 4 species were not inhibited by any of the mono- or polysaccharides used.
This revised version was published online in July 2006 with corrections to the Cover Date. 相似文献
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Functional and genetic plasticities of the poliovirus genome: quasi-infectious RNAs modified in the 5'-untranslated region yield a variety of pseudorevertants. 总被引:9,自引:4,他引:5 下载免费PDF全文
Poliovirus RNA species with nucleotides 564 to 571 deleted or with a secondary structure domain (positions 564 to 629) replaced by a shorter irregular oligonucleotide have been engineered previously; these RNAs have been considered quasi-infectious (yielding a single late revertant plaque) and dead, respectively (E. Pilipenko, A. Gmyl, Y. Svitkin, S. Maslova, A. Sinyakov, and V. Agol, Cell 68:119-131, 1992). By using large amounts of these RNAs for transfections, revertant clones with a great variety of genetic changes (point mutations, insertions of foreign sequences, short or extended deletions) were isolated. The pattern of these changes supported the notion that an appropriately spaced oligopyrimidine-AUG tandem is important for efficient poliovirus RNA translation. Structural features within and around this tandem modulated the initiation efficiency. The functional and genetic plasticities of the poliovirus genome are briefly discussed. 相似文献
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